Intimate Moisturizer

Women's healthVaginal drynessTopical

Intimate Moisturizer

RxPrescription onlyApplied to the skin · Once a day · Women's health · Vaginal dryness · Topical

Starting at $179/mo

A daily vulvar moisturizer with hyaluronic acid and vitamins A and E, for dryness and discomfort, especially around menopause. Hormone-free.

Choose your plan

Start treatment· $179/mo

Real prices from our pharmacy. Longer plans cost less per month and are billed up front. Pause or cancel anytime.

  • Hormone-free hydration
  • Daily use builds comfort over weeks
  • Gentle, fragrance-free base

Every plan includes

  • Personalized, physician-guided plan
  • Monthly plan
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
  • Physician-guided care
  • Ongoing, expert support
  • 100% online
  • Free, discreet shipping

What is it?

(hyaluronic acid moisturizer)

Hyaluronic acid holds water in the tissue; vitamins A and E support the skin barrier. It eases dryness without estrogen.

How it is taken
Applied to the skin
How often
Once a day
Form
Women's health · Vaginal dryness · Topical

Hormone-free

an option when estrogen is not wanted or not advised

For moderate to severe atrophy, low-dose vaginal estrogen is more effective; your physician can discuss it.

How it works,
week by week.

  1. Day 1

    A physician reviews your symptoms, cycle or menopause stage, medications and goals, and chooses the product.

  2. First uses

    Use as directed; notice how your body responds and any local sensation.

  3. Weeks 2-4

    Response becomes clearer. Daily moisturizers need a few weeks for full effect.

  4. Month 1

    Check-in: adjust the product, add or change hormones if needed.

  5. Beyond

    Regular reviews as your needs change.

What you may notice,
and when.

  • Desire and arousal

    support where it starts

  • Sensitivity

    better local response

  • Comfort

    less dryness and discomfort

  • Physician oversight

    a plan built around you

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

Safety first:
what to know before you start.

Important safety information and common side effects

These products are used externally or dissolved in the mouth. Common effects are local warmth, tingling or irritation; with the desire troche, nausea, flushing and headache. Creams containing sildenafil must never be used with nitrates. Do not use during pregnancy or breastfeeding without your physician's approval. Stop and contact us if you have burning, a rash, or unusual discharge.

The research behind
hyaluronic acid.

Hyaluronic acid holds water in tissue. Its vaginal use has been tested against estrogen cream in women with dryness, and in one open-label trial it worked about as well.

  • Against estriol84.44% vs 89.42%

    In 144 women with vaginal dryness, mostly postmenopausal, a hyaluronic acid gel improved symptoms in 84.44% of women after 10 applications over 30 days. Estriol cream improved them in 89.42%, with no statistically significant difference between them.

    Chen et al., Journal of Sexual Medicine 2013
  • Schedule tested10 applications

    The trial applied the gel every three days, ten times over 30 days. The product here is labelled for daily use over 60 days, a schedule that has not been trialled.

    Chen et al., Journal of Sexual Medicine 2013
  • Vitamins A and Eno trials

    We found no trial of this exact formula, nor of the vitamin A or vitamin E in it, for vaginal use. Their roles are skin-care roles, not proven vaginal outcomes.

    PubMed search, hyaluronic acid vaginal moisturizer (2026)

What the studies found

  • Vaginal dryness improved in 84.44% of women after 10 applications, close to estriol cream at 89.42% (Chen et al., Journal of Sexual Medicine 2013)
  • No significant difference from estriol cream, so it is an option that contains no estrogen (Chen et al., Journal of Sexual Medicine 2013)
  • Adverse events were minor, mainly vaginal infection and genital itching (Chen et al., Journal of Sexual Medicine 2013)

The trial was open-label, so neither the women nor the assessors were blinded. The estrogen comparison was estriol, a weaker estrogen. This product is a moisturizer, not an estrogen.

What this does not say

  • One open-label trial over 30 days; longer-term effects were not reported in the sources we found.
  • Symptoms were scored on a visual analogue scale, which is subjective.
  • The reported adverse events were vaginal infection and itching.

The research
behind it.

Studies of hyaluronic acid vaginal products show relief of dryness comparable to low-dose estrogen for some women.

Mild stinging can occur at first; stop if irritation persists.

Getting started
takes a few minutes.

  1. 1

    Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2

    Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3

    Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Start treatment

Frequently asked questions

Contact support
How do I use Intimate Moisturizer (Hyaluronic Acid / Vitamin A / Vitamin E)?

Applied to the skin, once a day. The starting prescription is 1 mL each time. Your physician sets your own dose and it is printed on your label.

Where do I apply it?

Vulvar area.

What exactly is in it?

Hyaluronic Acid, Vitamin A, Vitamin E.

How much arrives in each shipment?

1 bottle at the starting strength, shipped to your door from a licensed US pharmacy.

Can I use it with vaginal estrogen?

Yes, they can be used together; apply them at different times of day.

What causes low desire or arousal?

Hormones, stress, sleep, medications (especially antidepressants), relationship factors and menopause all play a part. A physician looks at the whole picture.

Do I need blood work?

Sometimes. If hormones may be involved, your physician may order tests before choosing a treatment.

Can I use these with birth control?

Yes. None of these products affect contraception.

Intimate moisturizer educational content reviewed by our physician

Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

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References

  1. 1.Bremelanotide for hypoactive sexual desire disorder: two randomized phase 3 trials. Obstet Gynecol, 2019
  2. 2.Hyaluronic acid vaginal gel versus estriol cream for vaginal dryness in postmenopausal women. PubMed

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.