Injection
GHK-Cu
A naturally occurring copper peptide studied for skin repair, firmness and healthy aging. Prescribed and dosed by a licensed physician.
Starting at $209/mo
Explore skin treatments
built around your goals.
Look good. Feel even better. Clinician-guided plans for your skin, designed to work on the root cause, so you can feel like the best version of you.
Feeling stuck shouldn’t be
your new normal.
Sun, age and hormones all change how your skin looks and feels.¹ Some of the treatments we use have been studied for decades, and their effects can be measured.²
Our in-house care team of U.S.-licensed physicians and nurse practitioners chooses the plan and the pace for your skin, then adjusts it as you progress so you are never left guessing what to do next.
- 1.Systematic review of acne impacts on quality of life and mental health (101 studies, 2014 to 2024), Layton et al., American Journal of Clinical Dermatology, 2025.
- 2.Tretinoin for photodamaged facial skin: systematic review and meta-analysis of randomized controlled trials, Huang HY, Lee LTJ, Dermatology Practical & Conceptual, 2025.
What the trials measure
in skin, over months and years.
- Fewer fine wrinkles8 trials
randomized trials with 1,361 adults, pooled: tretinoin cream reduced fine wrinkling versus the same cream without it (a difference of 0.41 on the trials' grading scale) over 16 to 48 weeks.
Huang & Lee, Dermatol Pract Concept 2025 - Better skin, by your account82%
of women said their skin had improved at week 24 on spironolactone, versus 63% on placebo (odds ratio 2.72). Trial of 410 women with persistent facial acne in England and Wales, taking 50 to 100 mg a day. The quality-of-life gain at week 12 was small: 1.27 points on the Acne-QoL symptom scale.
SAFA trial, BMJ 2023 - Clearer skin26 to 35%
of people had an improved Investigator Global Assessment score at week 12 on a topical retinoid plus benzoyl peroxide, versus 7 to 12% on vehicle. Pooled from 54 trials of US-approved topical retinoids, tretinoin among them, published 2008 to 2018.
Kolli et al., Am J Clin Dermatol 2019
Across 101 studies from Europe and North America, acne mostly affected the emotional and psychological side of quality of life, and weighed most on adults, women and people with more severe disease. Layton et al., Am J Clin Dermatol 2025
Trial results are with the studied medicines at their studied doses, alongside a clinician-guided routine. Compounded versions were not studied in these trials. They are averages, not a prediction of your result.
The right skin plan
is built around your skin.
Skin changes slowly, and so should the plan. Our fully in-house care team stays with you through each stage, adjusting your medicine, strength and pace as your skin responds.
We stay with you to protect the progress you make, guide you through setbacks, and adjust the plan as your skin responds, with plans starting at $79 a month.
Start hereWe study the parts of skin care
most routines skip.
A routine is only as good as the evidence behind it. Our physicians read the trials for each medicine we prescribe, including the ones that did not show what people hoped.
Every skin treatment,
in one place.
Real products and real prices from our pharmacy. Your physician helps you choose the medicine, the form and the dose.
Injections
1Measured doses you give yourself at home, usually once a week or once a day.
Capsules
2Taken by mouth with water.
Capsule
Spironolactone Capsules
Spironolactone slow-release capsules for hormonal acne and hirsutism in women. A potassium-sparing diuretic and androgen antagonist prescribed and dosed by a licensed physician.
30 capsules per month
Starting at $79/mo
Capsule
Doxycycline
Oral antibiotic (tetracycline) for acne and rosacea at low anti-inflammatory doses. Available as capsules and tablets.
30 doses per month
Starting at $99/mo
Creams
16Applied to the skin at the same time each day.
Cream
Hydroquinone / Kojic Acid / Hydrocortisone Cream
Triple depigmenting formula with hydroquinone, kojic acid, and hydrocortisone for stubborn hyperpigmentation and melasma.
Starting at $94/mo
Cream
Hydroquinone / Tretinoin / Hydrocortisone Cream
Classic Kligman formulation combining depigmenting, retinoid, and anti-inflammatory agents. Gold standard for melasma.
Starting at $94/mo
Cream
Hydroquinone Cream
Topical hydroquinone for hyperpigmentation and melasma. Depigmenting agent for dark spots and uneven tone.
Starting at $94/mo
Cream
Tretinoin / Niacinamide / Hyaluronic Acid Cream
Tretinoin combined with soothing niacinamide and hydrating hyaluronic acid for reduced irritation and better tolerance.
Starting at $94/mo
Cream
Tretinoin Cream
Topical retinoid cream for wrinkles, acne, and photoaging. Prescription-strength skin renewal.
Starting at $94/mo
Cream
Acne Cream with Tretinoin
Acne treatment combining antibiotics (clindamycin/erythromycin/ketoconazole) with tretinoin for faster clearance and post-acne healing.
Starting at $101/mo
Cream
Acne Cream
Triple-action topical for acne: antibiotic (clindamycin + erythromycin) and antifungal (ketoconazole). Covers bacterial and fungal acne.
Starting at $101/mo
Cream
Brightening Cream
Stronger prescription cream for stubborn melasma and dark spots: hydroquinone 6% with tretinoin, hydrocortisone, kojic acid and vitamins C and E. A short course, usually up to 8 weeks.
Starting at $109/mo
Cream
Clarity Cream
Acne and post-acne formula combining azelaic acid, niacinamide, clindamycin, and tretinoin. Anti-inflammatory and cell-renewing.
Starting at $109/mo
Cream
ClearTone Cream
Brightening and anti-inflammatory cream combining azelaic acid, hydroquinone, kojic acid, tranexamic acid, and niacinamide. For post-acne hyperpigmentation.
Starting at $109/mo
Cream
LuminEye Cream
Targeted eye cream combining GHK-Cu, caffeine, tranexamic acid, and hyaluronic acid. For dark circles and fine lines under eyes.
Starting at $109/mo
Cream
Vital C5 Cream
Antioxidant brightening cream with vitamin C, niacinamide, resveratrol, vitamin E, and hyaluronic acid. Morning use with sunscreen.
Starting at $109/mo
Cream
EOS Cream
Gentle anti-inflammatory cream with azelaic acid, niacinamide, hyaluronic acid, and low-dose tretinoin. For sensitive or reactive skin.
Starting at $116/mo
Cream
Refine PM Cream
Nighttime renewal cream with GHK-Cu, tretinoin, dexpanthenol, vitamin E, and hyaluronic acid. Advanced anti-aging and collagen support.
Starting at $116/mo
Cream
GHK-Cu Cream
Pure GHK-Cu cream for collagen stimulation and skin renewal. 30 mL pump.
Starting at $131/mo
Cream
GHK-Cu Brightening Cream
Prescription cream for dark spots and melasma: hydroquinone 6% with niacinamide, GHK-Cu and hyaluronic acid. Applied once a day at bedtime, in courses your physician sets.
Starting at $138/mo
Gels
2Applied to the skin.
Gel
Tretinoin 0.15% Gel
A prescription-strength retinoid gel you apply at night to clear acne and smooth fine lines and sun damage over time. Prescribed by a licensed physician.
Starting at $94/mo
Gel
HydroTone Gel
Hydrating and firming gel with niacinamide, dexpanthenol, vitamin E, and hyaluronic acid. For morning or evening use.
Starting at $94/mo
21 treatments in this area, all from our live catalog.
Questions,
answered.
Contact supportHow long until I see results?
Acne usually improves in two to three months; fine lines and tone take longer. The first weeks can look worse before they look better.
Is peeling normal?
Yes. Dryness, redness and peeling are common in the first weeks. Using it a few nights a week at first and a gentle moisturizer helps.
Can I use it while pregnant?
Topical retinoids are not used during pregnancy. Tell your physician if you are pregnant, planning to be or breastfeeding.
Do I need sunscreen?
Yes, every day. Retinoids and brightening creams make skin more sensitive to the sun, and the sun undoes their work on dark spots.
How is it billed?
Monthly, every 3 months or every 6 months; longer plans cost less per month. Shipping is free and you can pause or cancel anytime.
References
- 1.Guidelines of care for the management of acne vulgaris (American Academy of Dermatology). J Am Acad Dermatol, 2024 (Reynolds RV et al.)
Compounded medications are not FDA-approved and the FDA has not reviewed them for safety, efficacy, or quality. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.