Injection
Estradiol Cypionate
Long-acting estradiol injection for menopause and perimenopause symptoms and for gender-affirming hormone therapy, given every one to two weeks. Prescribed and dosed by a licensed physician.
Starting at $139/mo
Your symptoms have answers.
It’s hormonal, and your care starts there.
Hot flashes, bones, sexual health and mood can all move with hormones. We look at what you are experiencing and what matters to you, and build your plan around both.
Feeling off shouldn’t be
your new normal.
Perimenopause and menopause lower and shift estrogen, progesterone and testosterone, and the effects reach well beyond hot flashes.¹ Hormone therapy has been studied for decades, and the research is more careful than either the fear or the hype.²
Our in-house care team of U.S.-licensed physicians and nurse practitioners looks at your symptoms, your history and your goals, chooses the form and dose that fit, and checks back as your body changes.
- 1.The 2022 hormone therapy position statement of The North American Menopause Society, Menopause, 2022.
- 2.The Women’s Health Initiative randomized trials and clinical practice: a review, Manson JE et al., JAMA, 2024.
What hormone therapy can do
and what it cannot.
- Better bones24%
fewer confirmed osteoporotic fractures with daily conjugated estrogen plus progestin in 16,608 women aged 50 to 79, with a median treatment of 5.6 years.
WHI combined-therapy trial, JAMA 2003 - Fewer hot flashes75%
fewer hot flashes than placebo, on average, across 24 trials of 3,329 women lasting from 3 months to 3 years. Placebo also improves, so the true gap is smaller than the drop from the starting point.
Cochrane review, MacLennan et al., 2004 - Better arteries, if started early44%
slower thickening of the carotid artery wall, 0.0044 versus 0.0078 mm a year with oral estradiol versus placebo, in women who started within 6 years of menopause, over about 5 years. Women who started 10 years or more after menopause saw no difference.
ELITE trial, NEJM 2016
Across the WHI randomized trials, followed for up to 18 years, hormone therapy was not associated with a change in overall death rates for women aged 50 to 79. Manson et al., JAMA 2017
Trial results are with the studied medicines (conjugated estrogens, estradiol, medroxyprogesterone) at their studied doses, and they are averages, not predictions. Our products are compounded or generic versions, and the trials did not test them. The hot-flash figure is relative to placebo. The 44% is calculated from the two yearly rates reported by ELITE.
The right hormone plan
fits your body and your life.
Perimenopause and menopause are not one stage with one answer. Our team reviews your symptoms, your history and your goals, sets the form, dose and route with you, and adjusts them as your body changes.
We check in as your symptoms and goals change, and adjust your plan with you, with plans starting at $79 a month.
Start hereWe study the parts of women’s health
that symptoms do not show.
Hormones act on bones, blood vessels, the vagina, the bladder and the brain, not only on hot flashes. The research on each is uneven. We would rather show you the trials, with their limits, than promise more than they show.
Hormone therapy beyond hot flashes:
what the research showsBones, the heart, vaginal health and sexual desire: the trials, with their numbers and their limits.Read the researchHormone therapy and breast cancer risk:
what the trials foundEstrogen alone and with progestin, why the two differ, and how physicians weigh it.Read the research
what the research showsBones, the heart, vaginal health and sexual desire: the trials, with their numbers and their limits.Read the researchHormone therapy and breast cancer risk:
what the trials foundEstrogen alone and with progestin, why the two differ, and how physicians weigh it.Read the research
Every women's health treatment,
in one place.
Real products and real prices from our pharmacy. Your physician helps you choose the medicine, the form and the dose.
Injections
2Measured doses you give yourself at home, usually once a week or once a day.
Injection
Testosterone Cypionate - Women
Low-dose testosterone for women, a small weekly injection used mainly for low sexual desire after menopause. Prescribed and dosed by a licensed physician.
Starting at $99/mo
Dissolving tablets
5Dissolves under the tongue. No needles.
Dissolving tablet
BIEST (50:50) ODT
Bioidentical estrogen dissolving tablet (estriol and estradiol in 50:50 ratio). Orally disintegrating for fast absorption. Supports hormonal balance and menopausal symptoms.
30 tablets per month
Starting at $79/mo
Dissolving tablet
Progesterone ODT
Bioidentical progesterone in orally disintegrating tablet form. Supports hormonal balance and endometrial protection with sublingual absorption.
30 tablets per month
Starting at $79/mo
Dissolving tablet
BIEST (20:80) 0.05 mg ODT
A low-dose bioidentical estrogen (20% estriol, 80% estradiol) in a tablet that dissolves in the mouth, for hot flashes, night sweats and other menopause symptoms. Prescribed and dosed by a licensed physician.
30 tablets per month
Starting at $99/mo
Dissolving tablet
BIEST (20:80) 0.1 mg ODT
A stronger dose of bioidentical estrogen (20% estriol, 80% estradiol) in a dissolving tablet, for menopause symptoms not controlled by the lower dose. Prescribed and dosed by a licensed physician.
30 tablets per month
Starting at $99/mo
Dissolving tablet
Oxytocin ODT
Oxytocin in orally disintegrating tablet form. Supports sexual desire, bonding, and mood. Taken daily by mouth or before intimacy.
30 tablets per month
Starting at $129/mo
Troches
3A small lozenge that dissolves in the mouth.
Troche
Progesterone Troches
Bioidentical progesterone in a sublingual troche, taken at bedtime to balance estrogen, protect the uterine lining and support sleep. Prescribed and dosed by a licensed physician.
30 troches per month
Starting at $79/mo
Troche
Female Desire Troches
Sublingual troche for female sexual desire and arousal. Combines apomorphine, bremelanotide, oxytocin, and L-theanine for comprehensive support.
4, 8 or 12 troches per month
Starting at $59/mo
Troche
Oxytocin Troches
Oxytocin in troche (lozenge) form with creme de menthe flavoring. Supports sexual desire and bonding with pleasant taste.
30 troches per month
Starting at $129/mo
Tablets
1Taken by mouth with water.
Tablet
Estradiol Tablets
FDA-approved bioidentical estradiol tablets from commercial pharmaceutical manufacturer (not compounded). Taken daily by mouth for systemic hormone support.
30 tablets per month
Starting at $79/mo
Capsules
8Taken by mouth with water.
Capsule
BIEST / Progesterone Capsules
Combination bioidentical hormones (BIEST and progesterone) in oral capsules. Provides estrogen and progesterone balance for menopausal support.
30 capsules per month
Starting at $79/mo
Capsule
Estradiol Capsules
Bioidentical estradiol in oral immediate-release capsules. Taken daily by mouth for systemic hormone support.
30 capsules per month
Starting at $79/mo
Capsule
Progesterone Capsules
Bioidentical progesterone in sustained-release oral capsules. Supports hormonal balance and endometrial protection. Taken at bedtime.
30 capsules per month
Starting at $79/mo
Capsule
BIEST Capsules
Bioidentical estrogen (estriol and estradiol) in an oral capsule, for hot flashes, night sweats and other menopause symptoms. Prescribed and dosed by a licensed physician.
30 capsules per month
Starting at $89/mo
Capsule
DHEA / Pregnenolone Capsules
Combination bioidentical hormones (DHEA and pregnenolone) in oral capsules. Supports energy, mood, and hormone balance in both women and men.
30 capsules per month
Starting at $69/mo
Capsule
DHEA Capsules
Dehydroepiandrosterone (DHEA) in sustained-release capsules. Supports hormone balance, energy, and mood in both women and men. Taken in the morning.
30 capsules per month
Starting at $69/mo
Capsule
Pregnenolone Capsules
Pregnenolone, a precursor hormone in oral capsules. Supports cognitive function, mood, and hormone balance. Taken daily by mouth.
30 capsules per month
Starting at $69/mo
Capsule
7-Keto DHEA Capsules
7-Keto DHEA, a metabolite of DHEA that does not convert to testosterone or estrogen. Supports energy and metabolism without hormonal side effects.
30 capsules per month
Starting at $89/mo
Creams
11Applied to the skin at the same time each day.
Cream
BIEST (20:80) Cream
Bioidentical estrogen cream (estriol and estradiol in 20:80 ratio) applied topically. Supports hormonal balance and menopausal symptoms. Prescribed and dosed by a licensed physician.
Starting at $79/mo
Cream
BIEST (50:50) Cream
Bioidentical estrogen cream (estriol and estradiol in 50:50 ratio) applied topically. Supports hormonal balance and menopausal symptoms with equal estriol and estradiol content.
Starting at $79/mo
Cream
BIEST / Progesterone Cream
Combination bioidentical hormones (BIEST and progesterone) in topical cream. Provides estrogen and progesterone balance applied to skin.
Starting at $79/mo
Cream
Estradiol / Progesterone Cream
Combination bioidentical hormones (estradiol and progesterone) in topical cream. Provides estrogen and progesterone balance applied to skin.
Starting at $79/mo
Cream
Estradiol Cream
Bioidentical estradiol in topical cream form. Stronger estrogen component for menopausal symptom relief. Applied daily to skin.
Starting at $79/mo
Cream
Estriol Cream
Bioidentical estriol in topical cream form. Weaker estrogen component, often used for gentle hormone support. Applied daily to skin.
Starting at $79/mo
Cream
Progesterone Cream
Bioidentical progesterone in topical cream form. Supports hormonal balance and endometrial protection. Applied to skin daily.
Starting at $79/mo
Cream
Testosterone Cream for Women (Topi-Click)
Testosterone topical cream in a Topi-Click dispenser for women with low testosterone. Controlled substance, prescribed and dosed by a licensed physician.
Starting at $79/mo
Cream
Climax Cream
Topical cream for female sexual enhancement and orgasm support. Combination of arginine, ergoloid, pentoxifylline, sildenafil, and theophylline.
Starting at $116/mo
Cream
Ecstasy Cream for Her
Topical cream for female sexual arousal and pleasure. Contains oxytocin, theophylline, arginine, and sildenafil for enhanced sensation and response.
Starting at $138/mo
Cream
Intimate Moisturizer (Hyaluronic Acid / Vitamin A / Vitamin E)
Long-acting vulvar moisturizer for vaginal dryness, atrophy, and discomfort. Non-hormonal support for intimate health.
Starting at $179/mo
Vaginal creams
1Applied with an applicator.
Vaginal cream
Estradiol Vaginal Cream
Bioidentical estradiol in vaginal cream form. Treats atrophic vaginitis and vaginal dryness with local hormone therapy.
Starting at $79/mo
Vaginal inserts
1Inserted as directed.
Vaginal insert
Estradiol Vaginal Inserts
Bioidentical estradiol in vaginal insert form (10 mcg pellets). Treats atrophic vaginitis with sustained local hormone release.
Starting at $139/mo
32 treatments in this area, all from our live catalog.
Questions,
answered.
Contact supportIs hormone therapy safe?
For healthy women under 60 or within 10 years of menopause, The North American Menopause Society considers the benefits to outweigh the risks for most. Your physician reviews your personal history before prescribing.
What does bioidentical mean?
The hormone has the same molecular structure as the one your body makes, such as estradiol and progesterone. Compounded bioidentical hormones are not FDA-approved products.
Do I need progesterone?
If you have a uterus and take estrogen, yes: progesterone protects the lining of the uterus. If you've had a hysterectomy, usually not.
What about vaginal dryness?
Low-dose vaginal estrogen treats dryness and painful intercourse with very little absorbed into the rest of the body.
How is it billed?
Monthly, every 3 months or every 6 months; longer plans cost less per month. Shipping is free and you can pause or cancel anytime.
References
- 1.The 2022 hormone therapy position statement of The North American Menopause Society. Menopause, 2022
Compounded medications are not FDA-approved and the FDA has not reviewed them for safety, efficacy, or quality. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.