Injection
Gonadorelin
A copy of the brain's own GnRH signal that keeps the testes producing testosterone and sperm, used alongside testosterone therapy and in fertility care. Prescribed and dosed by a licensed physician.
Starting at $159/mo
TestosteroneInjectableFDA-approved
Testosterone Cypionate (Commercial)
RxPrescription onlyInjected into the muscle · Once a week · 50–100 mg · Testosterone · Injectable · FDA-approved
Starting at $149/mo
Commercial pharmaceutical-grade testosterone cypionate: FDA-approved, 200 mg/mL typical strength. Weekly or biweekly injection in MCT or grapeseed oil. Consistent pharmaceutical standards.
Choose your plan
Real prices from our pharmacy. Longer plans cost less per month and are billed up front. Pause or cancel anytime.
- FDA-approved pharmaceutical grade
- Consistent potency and purity
- Weekly or biweekly injection, steady levels
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
- Physician-guided care
- Ongoing, expert support
- 100% online
- Free, discreet shipping
What is commercial testosterone cypionate?
(kom-ER-shal)
Commercial testosterone cypionate is a pharmaceutical-grade formulation, FDA-approved for testosterone replacement therapy. Typical concentration: 200 mg/mL in MCT or grapeseed oil. Injected subcutaneously or intramuscularly, once or twice weekly. It meets rigorous pharmaceutical standards for purity and potency, unlike compounded formulations.
- How it is taken
- Injected into the muscle
- How often
- Once a week
- Dose range
- 50–100 mg
- Form
- Testosterone · Injectable · FDA-approved
FDA-approved
pharmaceutical-grade; meets USP standards
Commercial testosterone cypionate is regulated as a pharmaceutical product, ensuring consistent potency. It is available through licensed pharmacies. Weekly dosing provides steady testosterone levels.
How it works,
week by week.
Day 1
US-licensed physician reviews testosterone goals, medical history, and baseline labs (testosterone, hematocrit, PSA, lipids, BP).
Week 1
Teach injection technique. Start testosterone injection (weekly or biweekly). Most men learn to self-inject at home in minutes.
Week 4
Blood work checks testosterone level. If low, dose is increased. If target is reached, dose is maintained.
Month 2–3
Follow-up labs (testosterone, hematocrit, PSA, lipids, BP). Symptoms (energy, mood, libido, strength) reviewed.
Beyond
Testosterone monitored every 3–6 months; hematocrit and PSA every 6–12 months; BP every 3–6 months. Dose adjusted to keep testosterone in target range.
What you may notice,
and when.
Sustained energy and libido
steady testosterone supports mood and sexual function
Improved muscle and strength
testosterone builds lean mass over 4–12 weeks
Lab-monitored
hematocrit, PSA, BP, lipids tracked regularly
Home injection
self-injection at home once or twice weekly
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
Safety first:
what to know before you start.
Important safety information and common side effects
Injectable testosterone (cypionate, enanthate) carries the same safety profile as all testosterone therapy: elevated hematocrit (polycythemia), blood pressure elevation, PSA increase, reduced fertility during therapy, and clotting concerns. Polycythemia (high red cell count) is monitored with hematocrit tests every 6–12 months; if hematocrit rises above 54%, testosterone is held or reduced. PSA is checked at baseline and annually. Blood pressure is monitored every 3–6 months. Tell your physician about high blood pressure, blood clotting disorders, prostate cancer concerns, or fertility plans. Common injection-site reactions are mild (redness, soreness) and resolve in days. Stop and seek care for chest pain, shortness of breath, leg swelling, severe injection-site reactions, or signs of stroke.
The research behind
testosterone.
Testosterone replacement is well studied in men with diagnosed low testosterone, through large randomized trials. The evidence is strongest for gels and injections; it is weaker for troches, creams and hydrogels, which were not the forms tested in those trials.
- Heart safety7.0% vs 7.3%
TRAVERSE randomized more than 5,200 men aged 45 to 80 with symptoms and low testosterone, most with heart disease or high cardiovascular risk, to daily 1.62% gel or placebo for a mean of 33 months. Major cardiac events occurred in 7.0% on testosterone and 7.3% on placebo (hazard ratio 0.96, 95% CI 0.78 to 1.17). Atrial fibrillation was more frequent on testosterone.
TRAVERSE, NEJM 2023 - Sexual functionmoderate benefit
Testosterone Trials gave men aged 65 and older with low testosterone gel for one year, raising levels to the mid-normal range of younger men. Sexual activity, desire and erectile function improved. Vitality and walking distance did not improve, and the authors said the trial was too small to judge risks.
Snyder et al., NEJM 2016 - Blood sugar12% vs 21%
In the T4DM trial, 1,007 men with overweight or obesity in a lifestyle programme received intramuscular testosterone undecanoate or placebo for two years. At two years, 2-hour glucose of 11.1 mmol/L or higher was seen in 12% of the testosterone group and 21% of the placebo group (relative risk 0.59). This was a prevention outcome in men without a hypogonadism diagnosis, not a labelled use.
Wittert et al., Lancet Diabetes Endocrinol 2021
What the studies found
- Better sexual function in older men with low testosterone: libido and, to a lesser degree, erectile function improved (Testosterone Trials, Snyder et al., NEJM 2016).
- Walking distance improved in older men with low testosterone, though vitality did not (Testosterone Trials, Snyder et al., NEJM 2016; reviewed in Snyder et al., Endocr Rev 2018).
- Mood and depressive symptoms improved slightly, while cognition did not improve (Testosterone Trials, reviewed in Snyder et al., Endocr Rev 2018).
- Hemoglobin rose in older men with unexplained anemia: 54% of treated men gained 1.0 g/dL or more, against 15% on placebo (Roy et al., JAMA Intern Med 2017).
- Lowers blood-sugar progression in overweight or obese men with impaired glucose tolerance when combined with a lifestyle programme: 12% vs 21% reached a 2-hour glucose of 11.1 mmol/L or higher at two years (T4DM, Lancet Diabetes Endocrinol 2021).
Trial results are with the studied gel or injection at the studied dose, averages across groups, not predictions for one man. Compounded and brand products were not what these trials tested. Troches, creams and hydrogels deliver the hormone differently, so the trial numbers do not transfer directly.
What this does not say
- The Endocrine Society 2018 guideline recommends testosterone for men with symptoms and consistently low levels, aiming at mid-normal values; it does not recommend it for healthy men or for preventing disease (Bhasin et al., JCEM 2018, https://doi.org/10.1210/jc.2018-00229).
- Testosterone lowers sperm production in most men, which matters if fertility is wanted.
- Long-term outcome data are limited for most forms.
The research
behind it.
Commercial testosterone cypionate delivers physiologic testosterone replacement, meeting Endocrine Society guidelines for men with symptomatic hypogonadism.
Pharmaceutical-grade formulations undergo rigorous testing for potency, purity, and sterility, providing consistency that compounded formulations may not guarantee.
Testosterone beyond the gym:
what the trials show across body systemsSex drive, blood counts, bone, blood sugar and thinking: what the Testosterone Trials and T4DM found, and where the evidence stops.Read the researchTestosterone and the heart:
what TRAVERSE foundThe safety question most men ask first: heart events, fractures, prostate and blood counts, in the largest placebo-controlled trial of testosterone.Read the research
what the trials show across body systemsSex drive, blood counts, bone, blood sugar and thinking: what the Testosterone Trials and T4DM found, and where the evidence stops.Read the researchTestosterone and the heart:
what TRAVERSE foundThe safety question most men ask first: heart events, fractures, prostate and blood counts, in the largest placebo-controlled trial of testosterone.Read the research
Getting started
takes a few minutes.
- 1
Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
- 2
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
- 3
Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Frequently asked questions
Contact supportHow do I use Testosterone Cypionate (Commercial)?
Injected into the muscle, once a week. The starting prescription is 0.5 mL (50 mg) each time. Your physician sets your own dose and it is printed on your label.
What strengths does Testosterone Cypionate (Commercial) come in?
The pharmacy carries 2: 100 mg/mL, 200 mg/mL. Your physician chooses which one you get.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Is it a controlled substance?
Yes. The law requires a live video visit with the physician before it can be prescribed.
What is the difference between commercial and compounded testosterone?
Commercial testosterone is FDA-approved, pharmaceutical-grade, and meets USP (United States Pharmacopeia) standards for purity and potency. Compounded testosterone is prepared by a pharmacy to order, allowing customization but without FDA oversight. Your physician chooses based on availability, cost, and your needs.
How do I inject testosterone?
Your physician or nurse teaches you the technique in the first visit. Most men learn subcutaneous (under the skin) injection in seconds and feel comfortable within days. Intramuscular injection (into muscle) is also an option. Injections are done at home, typically once or twice per week.
What if my hematocrit rises?
Hematocrit (red blood cell count) can rise on testosterone. If it exceeds 54%, your physician may reduce your testosterone dose, have you donate blood, or pause therapy until it normalizes. Monitor hematocrit every 6–12 months.
Will testosterone affect my fertility?
Exogenous testosterone suppresses your body's natural testosterone production (testicular shutdown) and reduces sperm production. This is reversible: within 3–12 months of stopping testosterone, fertility usually returns. To preserve fertility during therapy, your physician may prescribe clomiphene or hCG alongside testosterone.
Testosterone cypionate (commercial) educational content reviewed by our physician
Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
More options
in this area.
Capsule
Anastrozole - Men
A low-dose aromatase inhibitor for men on testosterone therapy whose blood work shows high estradiol, easing breast tenderness and water retention. Slow-release capsule, prescribed and dosed by a licensed physician.
9 capsules per month
Starting at $63/mo
Capsule
Anastrozole Capsules
Anastrozole, an aromatase inhibitor used in men to control estrogen levels during testosterone therapy. Prescribed and dosed by a licensed physician.
9 capsules per month
Starting at $63/mo
Tablet
Anastrozole Tablets
FDA-approved anastrozole tablets, an aromatase inhibitor used at low doses in men on testosterone therapy whose estradiol runs high. Prescribed by a licensed physician only after blood work.
5 tablets per month
Starting at $63/mo
References
- 1.Endocrine Society Clinical Practice Guidelines for testosterone therapy: dosing, monitoring, and complications. J Clin Endocrinol Metab, 2018
- 2.TRAVERSE trial: testosterone replacement and cardiovascular outcomes in hypogonadal men. N Engl J Med, 2021
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.