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Glutathione Capsules

AntioxidantDetoxCellular

Glutathione Capsules

RxPrescription onlyTaken by mouth · Once a day · 100 mg · Antioxidant · Detox · Cellular

Starting at $99/mo

Glutathione (GSH): your body's master antioxidant, produced in every cell to neutralize oxidative stress. Oral liposomal form enhances absorption. Supports immune function, energy, and detoxification.

How many capsules per month?

MonthlyEvery 3 months
30 capsulesper month

You'll receive 30 capsules per month. $119 billed monthly. Cancel anytime.

Start treatment· $119/mo

Real prices from our pharmacy. Longer plans cost less per month and are billed up front. Pause or cancel anytime.

  • Your body's own antioxidant system at the cellular level
  • Liposomal form crosses intestinal barrier better than standard capsules
  • Supports immune function, energy, and recovery

Every plan includes

  • Personalized, physician-guided plan
  • 30 capsules per month, monthly and 3-month
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
  • Physician-guided care
  • Ongoing, expert support
  • 100% online
  • Free, discreet shipping

What is glutathione?

(gamma-glutamyl-cysteinyl-glycine, GSH)

Glutathione is a tripeptide (three amino acids bonded together) made by every cell in your body. It neutralizes free radicals and toxic compounds via the glutathione-S-transferase enzyme system. Glutathione levels decline with age, stress, and chronic illness. Oral GSH has poor bioavailability because it is broken down in the stomach; liposomal or acetyl-glutathione forms improve absorption. Some people report improved energy, immune function, and skin clarity with supplementation.

How it is taken
Taken by mouth
How often
Once a day
Dose range
100 mg
Form
Antioxidant · Detox · Cellular

Master

antioxidant made by every cell

Oral glutathione absorption is limited. Liposomal formulations, N-acetyl-L-cysteine (NAC, a precursor), or intravenous GSH achieve higher bioavailability. Discuss form and dose with your physician.

How it works,
week by week.

  1. Day 1

    Your physician reviews your energy, cognition, mood, medications, and health history. Discusses how glutathione or methylene blue support mitochondrial and antioxidant systems.

  2. Week 1

    Start with your prescribed dose of glutathione or methylene blue capsules. Take with food to improve tolerance. Expect blue urine if taking methylene blue.

  3. Weeks 2-4

    Some people notice improved energy, mood, or mental clarity. Others see no immediate change. Cellular repairs take time; be patient.

  4. Month 2

    Your physician checks in on energy, mood, cognition, and any side effects. Discuss timing, dose, or whether to continue or adjust.

  5. Beyond

    Cellular support compounds work best on a consistent schedule. Your physician reassesses every 3-6 months based on your response and evolving research.

What you may notice,
and when.

  • Improved energy

    especially with repeated dosing over weeks

  • Clearer thinking

    mental fog may lift gradually

  • Mood support

    emerging evidence in depression and anxiety

  • Cellular protection

    antioxidant and mitochondrial support

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

Safety first:
what to know before you start.

Important safety information and common side effects

Glutathione and methylene blue are generally well tolerated at recommended doses. Glutathione: no established upper limit; side effects are rare. Methylene blue: at therapeutic doses (5-20 mg daily) is safe, but do not combine with SSRIs, MAOIs, or tricyclic antidepressants due to serotonin syndrome risk. Tell your physician about all medications, especially psychiatric drugs. Methylene blue may reduce the efficacy of some antibiotic or chemotherapy drugs; discuss with your physician if on cancer treatment. Methylene blue can reduce oxygen saturation slightly; avoid in people with severe anemia or respiratory disease. Stop and seek care for signs of serotonin syndrome (rapid heart rate, confusion, muscle rigidity, hyperthermia) if using methylene blue with psychiatric medications.

The research behind
glutathione.

The body's main intracellular antioxidant, and it can be taken by mouth or injected. Oral trials in small groups of healthy adults show that blood levels can rise, but no trial has shown a health benefit. Injected glutathione has been tested only in a few small Parkinson's and skin-lightening studies.

  • Oral trial54 adults, 6 months

    250 or 1,000 mg a day against placebo for six months in 54 non-smoking adults. Blood glutathione rose at both doses. The trial measured blood levels, not disease or symptoms.

    Richie et al., Eur J Nutr 2015
  • Oral, no effect40 adults, 4 weeks

    500 mg twice a day against placebo for four weeks in healthy adults. Urinary markers of oxidative stress and red-cell glutathione did not change between the groups.

    Allen and Bradley, J Altern Complement Med 2011
  • Injected glutathionesmall Parkinson's pilot

    A randomized, double-blind pilot in Parkinson's disease found no significant difference from placebo in motor and daily-living scores. Its dose and size appear only in its abstract, so they are not repeated here. We found no injected trial with a health outcome in healthy adults.

    Hauser et al., Mov Disord 2009

What the studies found

  • Raises glutathione in the blood with daily oral doses. This is a biomarker, not a health result (54 adults, 6 months; Richie et al., Eur J Nutr 2015).
  • A company-funded pilot of 12 adults reported higher blood glutathione and natural-killer cell activity within two weeks of liposomal glutathione, by up to 400%. No independent repeat was found (Sinha et al., Eur J Clin Nutr 2018).
  • No benefit on oxidative-stress markers was found with 500 mg twice a day for four weeks (40 adults; Allen and Bradley, J Altern Complement Med 2011).
  • Animal and cell work suggests a role in antioxidant defence. No human health benefit has been shown (mechanistic work, unproven in people).
Read the full research

The trials here measured blood levels or markers of oxidative stress, not health outcomes, so none shows a benefit. No trial cited here tests the product sold here. GlyNAC, a glycine and N-acetylcysteine combination, is a different intervention with its own trials and is not counted here.

What this does not say

  • No trial has shown that oral or injected glutathione improves a clinical outcome.
  • The immune result of the 54-adult trial (natural-killer cell activity) appears only in its abstract and is not confirmed, so it is not used here. Its funding could not be confirmed either.
  • The liposomal pilot (12 adults) was funded by the company that supplies its product. A liposomal form is a different product from the oral trials above.

The research
behind it.

Glutathione is the primary intracellular antioxidant. Low levels correlate with aging, neurodegenerative disease, and immune dysfunction. Boosting GSH is a plausible strategy for cellular repair.

Oral GSH bioavailability is poor; most clinical evidence comes from IV or liposomal forms or from NAC precursor studies. Oral liposomal GSH shows some evidence for immune and detox support.

NAD+ and cellular energy:
what the trials showNAD+ precursors, NAD+ injections, glutathione and methylene blue: what has been tested in people, and what has not.Read the researchFatigue:
what to test before you treatB12, thyroid, sleep apnea, hormones and mood: the causes behind tiredness, what the labs show, and how common each one is.Read the research

Getting started
takes a few minutes.

  1. 1

    Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2

    Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3

    Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Start treatment

Frequently asked questions

Contact support
How do I take Glutathione Capsules?

Taken by mouth, once a day. The starting prescription is 1 capsule (100 mg) each time. Your physician sets your own dose and it is printed on your label.

How much arrives in each shipment?

30 capsules at the starting strength, shipped to your door from a licensed US pharmacy.

Why not just take NAC if glutathione is broken down?

NAC is a precursor; your body converts it to glutathione. NAC has strong clinical evidence for immune and respiratory support. GSH and NAC complement each other. Your physician chooses based on your health goals and tolerance.

When will I feel better?

Energy and mood changes can take 2-4 weeks with consistent dosing. Cognitive benefits may take months to notice. Some people respond quickly; others need sustained use. Keep a symptom log.

Can I combine glutathione and methylene blue?

These are separate compounds with different mechanisms. Some physicians use both; others prefer one. Discuss your health goals and medication history with your physician to decide the best approach.

Are there interactions with my other medications?

Methylene blue has significant interactions with psychiatric medications (SSRIs, MAOIs, tricyclics) due to serotonin syndrome risk. Tell your physician about every medication you take.

Is this supported by clinical evidence?

Glutathione and methylene blue show promise in early-stage and animal studies. Human clinical trials are limited. Your physician uses these based on mechanistic reasoning and emerging evidence, not established clinical practice.

Glutathione educational content reviewed by our physician

Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

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References

  1. 1.Glutathione: a master antioxidant and cellular regulator. J Nutr Biochem, 2007
  2. 2.Methylene blue as a mitochondrial and neuroprotective agent. Redox Biol, 2017

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.