Tablet
Ezetimibe Tablets
Ezetimibe, a cholesterol-absorption inhibitor, used to lower cholesterol levels. Commercial formulation prescribed and dosed by a licensed physician.
30 tablets per month
Starting at $69/mo
EnergyHeartMitochondrial
Coenzyme Q10 Capsules
RxPrescription onlyTaken by mouth · Once a day · 100 mg · Energy · Heart · Mitochondrial
Starting at $109/mo
Coenzyme Q10: mitochondrial enzyme cofactor for cellular energy and heart function. Levels decline with age and statin use. Oral capsule; ubiquinol form absorbs better.
How many capsules per month?
MonthlyEvery 3 months
30 capsulesper month
You'll receive 30 capsules per month. $129 billed monthly. Cancel anytime.
Real prices from our pharmacy. Longer plans cost less per month and are billed up front. Pause or cancel anytime.
- Powers mitochondrial energy production in every cell
- Supports heart muscle function and endurance
- Statin users especially benefit from Q10 replacement
Every plan includes
- Personalized, physician-guided plan
- 30 capsules per month, monthly and 3-month
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
- Physician-guided care
- Ongoing, expert support
- 100% online
- Free, discreet shipping
What is coenzyme Q10?
(ubiquinone or ubiquinol)
Coenzyme Q10 is an enzyme cofactor made by your body that sits in the inner mitochondrial membrane and carries electrons in the energy-producing chain. Your cells use it to make ATP, the currency of cellular energy. Q10 levels decline with age and with statin therapy (statins inhibit Q10 synthesis). Oral Q10 supplementation increases serum levels and may restore cellular energy.
- How it is taken
- Taken by mouth
- How often
- Once a day
- Dose range
- 100 mg
- Form
- Energy · Heart · Mitochondrial
Age-related
Q10 levels drop 30-40% by age 60
Statins speed this decline. Statin users often benefit from Q10 supplementation; your physician may recommend 100-300 mg daily.
How it works,
week by week.
Day 1
Your physician reviews your diet, lifestyle, lab values (including vitamin D level), and goals. Discusses which vitamins fill gaps and how to time them with meals.
Week 1
Start your daily vitamins with breakfast or as directed. Take fat-soluble vitamins (D, K, CoQ10, fish oil) with food to improve absorption.
Weeks 2-4
Most people tolerate vitamins well. Some notice subtle energy shifts or better joint comfort. Keep a symptom log.
Month 2-3
Your physician may check follow-up labs (vitamin D level, if supplementing D) to confirm optimal dosing.
Beyond
Vitamins work best on a consistent daily schedule. Annual labs and check-ins ensure your regimen matches your current needs.
What you may notice,
and when.
Better energy
especially if you were deficient
Stronger bones
D and K work synergistically over months
Reduced inflammation
fish oil and Q10 support recovery
Improved endurance
Q10 and fish oil support exercise capacity
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
Safety first:
what to know before you start.
Important safety information and common side effects
Vitamins D, K, CoQ10, and fish oil are generally well tolerated at recommended doses. D3 at very high doses (over 10,000 IU daily long-term) can raise serum calcium; your physician sets your dose. K2 is safe; no upper limit is established. Q10 is safe; high doses may cause mild GI upset or insomnia. Fish oil can thin blood slightly at high doses; tell your physician if you take anticoagulants or antiplatelet drugs. Fish oil may cause burping or GI upset in some people. Stop and seek care for signs of hypercalcemia (nausea, vomiting, confusion) or unusual bleeding.
The research behind
coenzyme Q10.
Coenzyme Q10 is a molecule the body makes and uses in cell energy production. Its outcome evidence comes from one large trial in heart failure; for healthy adults the evidence is not outcome-based.
- Heart failureFewer major events
Q-SYMBIO randomized 420 people with moderate to severe heart failure to 100 mg of CoQ10 three times a day or placebo, on top of standard care, for 2 years. Major cardiovascular events were 15% vs 26% (hazard ratio 0.50, 95% CI 0.32 to 0.80).
Mortensen et al., JACC Heart Fail 2014 (Q-SYMBIO) - Early monthsNo difference at 16 weeks
In the same trial there was no significant difference between CoQ10 and placebo at 16 weeks; the separation appeared over the 2-year follow-up.
Mortensen et al., JACC Heart Fail 2014 (Q-SYMBIO) - Single trialOne trial, composite endpoint
The result rests on this one trial, and its primary endpoint was a composite of cardiovascular events, not all-cause death. Death rates were also lower with CoQ10, but those were secondary outcomes.
Mortensen et al., JACC Heart Fail 2014 (Q-SYMBIO)
What the studies found
- Fewer major heart events over 2 years in people with heart failure (Q-SYMBIO, JACC Heart Fail 2014)
- Fewer deaths and fewer heart-failure hospital stays in the same trial (Q-SYMBIO, JACC Heart Fail 2014)
- Reduced muscle pain, weakness, cramps and tiredness in statin users, in a pooled meta-analysis of 12 trials (Qu et al., JAHA 2018)
Q-SYMBIO tested 300 mg a day in heart failure, not in healthy adults. The capsules sold here are not the trial product in every respect, and they have not been tested for healthy people.
What this does not say
- Only heart failure was tested; healthy adults are not covered by this trial.
- The primary endpoint was a composite, not death alone.
- A single trial is not a settled answer.
The research
behind it.
Q10 is essential for ATP synthesis; low levels correlate with age-related fatigue and reduced exercise tolerance. Supplementation can help restore energy in deficient individuals.
Some studies show Q10 benefits heart muscle function in people with heart disease or heart failure. The ubiquinol form (reduced Q10) absorbs better than ubiquinone.
NAD+ and cellular energy:
what the trials showNAD+ precursors, NAD+ injections, glutathione and methylene blue: what has been tested in people, and what has not.Read the researchFatigue:
what to test before you treatB12, thyroid, sleep apnea, hormones and mood: the causes behind tiredness, what the labs show, and how common each one is.Read the research
what the trials showNAD+ precursors, NAD+ injections, glutathione and methylene blue: what has been tested in people, and what has not.Read the researchFatigue:
what to test before you treatB12, thyroid, sleep apnea, hormones and mood: the causes behind tiredness, what the labs show, and how common each one is.Read the research
Getting started
takes a few minutes.
- 1
Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
- 2
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
- 3
Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Frequently asked questions
Contact supportHow do I take CoQ10 Capsules?
Taken by mouth, once a day. The starting prescription is 1 capsule (100 mg) each time. Your physician sets your own dose and it is printed on your label.
How much arrives in each shipment?
30 capsules at the starting strength, shipped to your door from a licensed US pharmacy.
Should I take Q10 if I am on a statin?
Many physicians recommend it. Statins reduce Q10 synthesis in your body, which may contribute to statin-related muscle pain and fatigue. Q10 supplementation (100-300 mg daily) may restore energy and reduce muscle symptoms. Discuss with your physician.
Can I take all these vitamins together?
Yes. D, K, CoQ10, and fish oil are safe to take together. Take them all with food to improve absorption. Separate any other medications by 2-4 hours from fish oil if you are on blood thinners.
How do I know if I am deficient?
Vitamin D deficiency is easy to test; your physician can check your serum 25-hydroxyvitamin D level. K, Q10, and omega-3 deficiencies are harder to test precisely, but dietary assessment and symptoms guide supplementation.
Are vitamins from food better than supplements?
Ideally, you get vitamins from food. But modern diets often fall short. Supplements fill gaps. A varied diet plus targeted supplements usually works best.
How long until I notice a change?
Energy shifts may appear in weeks; bone and joint benefits take months to become obvious. Be patient and consistent; improvements build gradually.
Coenzyme Q10 educational content reviewed by our physician
Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
More options
in this area.
Capsule
Fish Oil Capsules
Fish Oil supplements rich in omega-3 fatty acids for cardiovascular health, inflammation support, and overall wellness.
30 capsules per month
Starting at $79/mo
Capsule
Vitamin D3 / K2 Capsules
Vitamin D3 and K2 combination for bone health, cardiovascular support, and immune function. Recommended by physicians for wellness optimization.
9 capsules per month
Starting at $53/mo
Capsule
Vitamin D3 Capsules
Vitamin D3, essential for bone health, immune function, and overall wellness. Prescribed and dosed by a licensed physician.
30 capsules per month
Starting at $63/mo
References
- 1.Vitamin D supplementation and bone density in older adults. JAMA, 2022
- 2.Omega-3 fatty acids and cardiovascular disease: epidemiology and effects. Circulation, 2019
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.